pte20240206015 Medical/Health, Research/Development
According to a US comparative analysis, cardiometabolic health indicators are improving significantly
Salmon: Proven Health-Enhancing Effects (Photo: pixabay.com, Robson veneziani)
Salmon contains unique compounds that have been linked to improved cardiometabolic health indicators, such as lower cholesterol levels. This is the result of a study led by University of Colorado Anschutz Medical Campus. Researchers examined the health benefits of this type of fish in the context of the Mediterranean diet, which focuses on healthy oils and fats. Details are published in the “Journal of Nutrition”.
Salmon twice a week
As part of the study, participants ate two servings of salmon per week — two over five-week periods. Nutrimetabolomics is a current way of studying nutrients in food. Salmon contains 508 dietary compounds. It includes 237 metabolites specific to this fish. When salmon is eaten as part of the Mediterranean diet, the body receives at least 48 of these compounds, along with 30 metabolites that are produced during digestion or other chemical processes in the body.
Four of these metabolites were associated with significant improvements in cardiometabolic health indicators, or CHI. The researchers conducted a secondary analysis of an existing randomized trial involving 41 individuals. They ate a Mediterranean diet for two five-week periods. There was a gap of four weeks between the two periods. Participants were between the ages of 30 and 69 and were obese or overweight. However, none suffered from metabolic diseases such as type 2 diabetes or other serious conditions.
The researchers determined CHI values and collected blood plasma samples before and after the study. The analysis showed an association with salmon, which was not detected with other foods. It is named “Salmon FSC”. In the next step, relevant metabolites were identified using machine learning. Proven benefits include reductions in total cholesterol, LDL cholesterol, triglycerides, and apolipoprotein B, which is considered an indicator of heart disease.